Overweight in Older Adults: A Follow-Up of Fifteen Years of the SABE Survey.

Despite extensive research on overweight and obesity, there are few studies that present longitudinal statistical analyses among non-institutionalized older adults, particularly in low- and middle-income countries. This study aimed to assess the prevalence and factors associated with excess weight in older adults from the same cohort over a period of fifteen years. A total of 264 subjects aged (≥60 years) from the SABE survey (Health, Wellbeing and Aging) in the years 2000, 2006, 2010, and 2015 in the city of São Paulo, Brazil, were evaluated. Overweight was assessed by a BMI of ≥28 kg/m2. Multinomial logistic regression models adjusted for sociodemographic and health data were used to assess factors associated with excess weight. After normal weight, overweight was the most prevalent nutritional status in all evaluated periods: 34.02% in 2000 (95%CI: 28.29-40.26); 34.86% in 2006 (95%CI: 28.77-41.49%); 41.38% in 2010 (95%CI: 35.25-47.79); 33.75% in 2015 (95%CI: 28.02-40.01). Being male was negatively associated with being overweight in all years (OR: 0.34 in 2000; OR: 0.36 in 2006; OR: 0.27 in 2010; and OR: 0.43 in 2015). A greater number of chronic diseases and worse functionality were the main factors associated with overweight, regardless of gender, age, marital status, education, physical activity, and alcohol or tobacco consumption. Older adults with overweight and obesity, a greater number of chronic diseases, and difficulties in carrying out daily tasks required a greater commitment to healthcare. Health services must be prepared to accommodate this rapidly growing population in low- and middle-income countries.

Health conditions and weight change among the older adults over ten years of the SABE Survey. / Condições de saúde e mudança de peso de idosos em dez anos do Estudo SABE.

OBJECTIVE: To analyze the relationship between health conditions and weight changes among elderly people monitored by the SABE Survey over a ten-year period in São Paulo/SP. METHODS: This was a longitudinal study that followed (2000-baseline, 2006 and 2010) change in body weight (outcome variable) and associated health conditions (exposure variables) in the elderly (n=571); multinomial logistic regression analyses were employed. RESULTS: Average weight increase in the evaluated period was 29.0%. 34.0% (2006) and 12.5% (2010) lost weight and 18.2% (2006) and 39.9% (2010) gained weight. Prevalence of chronic diseases increased from 34.1% (2000) to 51.9% (2006) and 60.1% (2010). Older people with weight gain also rated their overall health as poorer in 2006 (RR:3.15; 95%CI 1.21;8.17) and 2010 (RR:2.46; 95%CI 1.02;5.94). The higher numbers of diseases (RR:2.12; 95%CI 1.00;4.46) and hospitalizations (RR:3.50; 95%CI 1.40;8.72) were associated with a decrease in weight in 2010. CONCLUSION: Weight changes are related to poorer health status among the elderly.

Health conditions and change weight of older adults in ten years of the SABE Survey / Condiciones de salud y cambio de peso de personas mayores en diez años del Estudio SABE / Condições de saúde e mudança de peso de idosos em dez anos do Estudo SABE

Objective. To analyze the relationship between health conditions and weight changes among the elderly, SABE Survey, over a period of ten years. Methods. Longitudinal study that followed (2000-baseline, 2006 and 2010) the change in body weight (outcome variable) and associated health conditions (exposure variables) in the elderly (n=571); multinomial logistic regression analyzes were employed. Results. The average weight increase in the evaluated period was 29.0%. 34.0% (2006) and 12.5% (2010) lost weight and 18.2% (2006) and 39.9% (2010) gained weight. The prevalence of chronic diseases increased from 34.1% (2000) to 51.9% (2006) and 60.1% (2010). Older people with weight gain also rated their overall health worse in 2006 (RR:3.15; 95%CI 1.21;8.17) and 2010 (RR:2.46; 95%CI 1.02;5.94). The highest number of diseases (RR:2.12; 95%CI 1.00;4.46) and hospitalizations (RR:3.50; 95%CI 1.40;8.72) were associated with a decrease in weight in 2010. Conclusion. Weight changes are related to worse health status among the elderly.

Objetivo. Analisar a relação das condições de saúde com a mudança de peso entre idosos, do Estudo SABE, em um período de dez anos. Métodos. Estudo longitudinal que acompanhou (2000-baseline, 2006 e 2010) a mudança do peso corporal (variável desfecho) e condições de saúde associadas (variáveis de exposição) em idosos (n=571); análises de regressão logística multinomial foram empregadas. Resultados. O aumento médio de peso no período foi de 29,0%. Perderam peso 34,0% (2006) e 12,5% (2010); e ganharam peso 18,2% (2006) e 39,9% (2010). A prevalência de doenças crônicas aumentou de 34,1% (2000) para 51,9% (2006) e 60,1% (2010). Idosos com aumento de peso avaliaram pior sua saúde geral em 2006 (RR:3,15; IC95%1,21;8,17) e 2010 (RR:2,46; IC95%1,02;5,94). Maior número de doenças (RR:2,12; IC95%1,00;4,46) e internações (RR:3,50; IC95%1,40;8,72) associaram-se a diminuição de peso em 2010. Conclusão. Mudanças de peso estão relacionadas a um pior estado de saúde entre idosos.

Condições de saúde e mudança de peso de idosos em dez anos do Estudo SABE / Condiciones de salud y cambio de peso de personas mayores en diez años del Estudio SABE / Health conditions and weight change among the older adults over ten years of the SABE Survey

Objetivo: Analisar a relação das condições de saúde com a mudança de peso entre idosos em um período de dez anos em São Paulo/SP. Métodos: Estudo longitudinal que acompanhou (2000-baseline, 2006 e 2010) a mudança do peso corporal (variável desfecho) e condições de saúde associadas (variáveis de exposição) em idosos (n=571); análises de regressão logística multinomial foram empregadas. Resultados: O aumento médio de peso no período foi de 29,0%. Perderam peso 34,0% (2006) e 12,5% (2010); e ganharam peso 18,2% (2006) e 39,9% (2010). A prevalência de doenças crônicas aumentou de 34,1% (2000) para 51,9% (2006) e 60,1% (2010). Idosos com aumento de peso avaliaram pior sua saúde geral em 2006 (RR:3,15; IC95% 1,21;8,17) e 2010 (RR:2,46; IC95% 1,02;5,94). Maior número de doenças (RR:2,12; IC95% 1,00;4,46) e internações (RR:3,50; IC95% 1,40;8,72) associaram-se a diminuição de peso em 2010. Conclusão: Mudanças de peso estão relacionadas a um pior estado de saúde entre idosos.

Objetivo: Analizar la relación entre las condiciones de salud y el cambio de peso entre adultos mayores durante un período de diez años en São Paulo/SP. Métodos: Estudio longitudinal (2000-baseline, 2006 y 2010) que siguió el cambio en el peso corporal (variable de resultado) y las condiciones de salud asociadas (variables de exposición) en adultos mayores (n=571); se emplearon análisis de regresión logística multinomial. Resultado: El aumento de peso promedio en el período evaluado fue del 29,0%. Un 34,0% (2006) y 12,5% (2010) perdieron peso; 18,2% (2006) y 39,9% (2010) ganaron peso. La prevalencia de enfermedades crónicas aumentó del 34,1% (2000) para 51,9% (2006) y 60,1% (2010). Las personas mayores con aumento de peso calificaron su salud general peor en 2006 (RR:3,15; IC95% 1,21;8,17) y 2010 (RR:2,46; IC95% 1,02;5,94). El mayor número de enfermedades (RR:2,12; IC95% 1,00;4,46) y hospitalizaciones (RR:3.50; IC95% 1,40;8,72) se asociaron con una disminución del peso en 2010. Conclusión: Los cambios de peso están relacionados con un peor estado de salud entre los adultos mayores.

Objective: To analyze the relationship between health conditions and weight changes among elderly people monitored by the SABE Survey over a ten-year period in São Paulo/SP. Methods: This was a longitudinal study that followed (2000-baseline, 2006 and 2010) change in body weight (outcome variable) and associated health conditions (exposure variables) in the elderly (n=571); multinomial logistic regression analyses were employed. Results: Average weight increase in the evaluated period was 29.0%. 34.0% (2006) and 12.5% (2010) lost weight and 18.2% (2006) and 39.9% (2010) gained weight. Prevalence of chronic diseases increased from 34.1% (2000) to 51.9% (2006) and 60.1% (2010). Older people with weight gain also rated their overall health as poorer in 2006 (RR:3.15; 95%CI 1.21;8.17) and 2010 (RR:2.46; 95%CI 1.02;5.94). The higher numbers of diseases (RR:2.12; 95%CI 1.00;4.46) and hospitalizations (RR:3.50; 95%CI 1.40;8.72) were associated with a decrease in weight in 2010. Conclusion: Weight changes are related to poorer health status among the elderly.

O papel da concentração salivar e sérica da proteína SLPI (inibidor de protease secretada por leucócitos) na progressão do carcinoma epidermoide da cavidade bucal / The Role of Tumor Expression and Salivary and Serum Concentration of Protein SLPI (Protein Inhibitor Secreted by Leukocytes) in Progression of Squamous Cell Carcinoma of the Oral Cavity

Introdução: A avaliação dos processos inflamatórios em pacientes com tumores de boca é assunto atual na literatura científica. Poucos estudos, entretanto avaliaram a expressão da Proteína Inibidora de Protease Secretada por Leucócito (SLPI), marcador específico de inflamação, em pacientes com câncer de boca Objetivos: 1.Descrever a frequência da concentração de SLPI salivar e sérica em pacientes com câncer bucal. 2. Avaliar a associação dessas concentrações com características clínicas, sociodemográficas e de estilo de vida. Metodologia: Realizou-se a quantificação de SLPI em soro por meio do teste ELISA em pacientes com carcinoma epidermoide da cavidade bucal atendidos no Hospital Heliópolis da Secretaria de Estado da Saúde do Estado de São Paulo no período entre 2011 e 2017. Dados relativos a estadiamento do tumor, características sócio demográficas dos pacientes, hábitos alimentares e estilo de vida foram coletados por meio de prontuários médicos e questionários aplicados aos pacientes. Foram realizados teste de correlação de Spearman e teste qui-quadrado para testar possíveis associações. Resultados: Foram encontradas: correlação positiva entre SLPI em saliva maços-ano de tabagismo (p=0,03) e correlação negativa entre SLPI bochecho para frequência no consumo de carne vermelha (p=0,01). A quantificação de SLPI em soro por quartis apresentou associação com significância estatística para escolaridade (maior proporção de pessoas com ensino médio completo no quartil mais baixo de SLPI), frequência de escovação dentária (maior proporção de pessoas que escovam os dentes mais do que uma vez por dia no quartil com maior SLPI) e estadiamento patológico (2º quartil com maior proporção de estadiamentos 3 e 4). Na avaliação de SLPI em saliva e bochecho, houve associação com o consumo de carne vermelha, havendo indivíduos com consumo mais baixo apenas nos quartis mais superiores de SLPI Conclusão: Este estudo concorda com a hipótese de que o SLPI em pacientes com câncer de boca se relaciona com estilo de vida e estadiamento da lesão

Introduction: The evaluation of inflammatory processes in patients with oral tumors is a current topic in the scientific literature. Few studies, however, have evaluated the expression of the Leukocyte Secreted Protein Inhibitor Protein (SLPI), a specific marker of inflammation in patients with oral cancer. Objectives: 1. To describe the frequency of salivary and serum SLPI in patients with oral cancer. 2. To evaluate the association of these concentrations with clinical, sociodemographic and lifestyle characteristics. Methodology: Serum SLPI was quantified by ELISA in patients with squamous cell carcinoma of the oral cavity treated at the Hospital Heliópolis of the State Health Department of the State of São Paulo in the period between 2011 and 2017. Data on staging of the tumor, socio-demographic characteristics of patients, eating habits and lifestyle were collected through medical records and questionnaires applied to patients. Spearman\'s correlation test and chi-square test were performed to test possible associations. Results: There was a positive correlation between SLPI in saliva and malnutrition SLPI (p = 0.03). The quantification of SLPI in serum by quartiles was associated with statistical significance for schooling (higher proportion of people with complete secondary education in the lowest quartile of SLPI), frequency of toothbrushing (a higher proportion of people brushing their teeth more than once per day in quartile with higher SLPI) and pathological staging (2nd quartile with a higher proportion of stages 3 and 4). In the evaluation of SLPI in saliva and mouthwash, there was an association with red meat consumption, with individuals with lower consumption only in the higher quartiles of SLPI. Conclusion: This study agrees with the hypothesis that SLPI in patients with oral cancer is related to lifestyle and staging of the lesion